Back to top hameln pharmaceuticals ltd contact details. Cyclizine is a histamine H 1 receptor antagonist of the piperazine class which is characterised by a low incidence of drowsiness. In this article arrow-down Setting up the syringe driver arrow-down Drugs used in the syringe driver arrow-down Drug compatibility arrow-down Problems with syringe drivers. By continuous intravenous infusion, or by subcutaneous infusion. System Organ Class Frequency Adverse reactions Blood and lymphatic system disorders Not known Agranulocytosis, leucopenia, haemolytic anaemia, thrombocytopenia. Show table of contents Hide table of contents 1. Although there are no data available, patients should be cautioned that cyclizine may have additive effects with alcohol and other central nervous system depressants, e.
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To view the changes to a medicine you must sign up and log in. By rectum For Child 2—5 years In such patients, syfinge may cause a fall in cardiac output associated with increases in heart rate, mean arterial pressure and pulmonary wedge pressure. Cardiac disorders Not known Tachycardia palpitations, arrhythmias see section 4.
Hepatic dysfunction see section 4. Hypersensitivity to the active substance or to any of the excipients listed in section 6. Hepatobiliary disorders Hepatic dysfunction see section 4. General disorders and administration site conditions Not known Asthenia Injection site reactions including vein tracking, erythema, pain, thrombophlebitis and blisters.
This medicinal product is indicated in adults for the prevention and treatment of nausea and vomiting cyckizine Agranulocytosis, leucopenia, haemolytic anaemia, thrombocytopenia. Symptoms Symptoms of acute toxicity from cyclizine arise from peripheral anticholinergic effects and effects on the central nervous system. Subcutaneous SC drug infusion by portable syringe driver has cycllizine a significant impact on pain management [ 1 ]. Syringe Drivers In this article Setting up the syringe driver Odse used in the syringe driver Drug compatibility Problems with syringe drivers.
Pregnancy In the absence of any definitive human data, the use of cyclizine in pregnancy is not advised.
Cyclizine Lactate 50 mg/ml Injection
Hepatic dysfunction see section 4. Assess your symptoms online with our free symptom checker.
Cyclizine is contraindicated in the presence of acute alcohol intoxication. To view the changes to a medicine you must sign up and log in. As with other anticholinergic agents, cyclizine may precipitate incipient glaucoma and it should be used with caution and appropriate monitoring in patients with glaucoma, urinary retention, obstructive disease of the gastrointestinal tract, hepatic disease, pheochromocytoma, hypertension, epilepsy and in males with possible prostatic hypertrophy.
Renal and urinary disorders Not known Urinary retention Respiratory, thoracic dosw mediastinal disorders Not known Bronchospasm, apnoea Skin and subcutaneous tissue disorders Not known Urticaria, pruritus, drug rash, angioedema, allergic skin reactions, fixed drug eruption, photosensitivity Vascular disorders Not known Hypertension, hypotension.
Each pack contains 5 or 10 ampoules. For administration by mouthtablets may be crushed. It may inhibit the part of the midbrain known collectively as the emetic centre. Disorientation, restlessness or agitation, nervousness, euphoria, insomnia and auditory and visual hallucinations have been reported, particularly when dosage recommendations have been exceeded.
Posology Adults The recommended dose is 50 syringr intramuscularly or intravenously up to three times daily.
CYCLIZINE | Drug | BNF content published by NICE
Hii guys,My grandfather 90 years old. In the management of acute overdosage with Valoid, gastric lavage and supportive measures for respiration and circulation should be performed if necessary. Urticaria, pruritus, drug rash, angioedema, allergic skin reactions, fixed drug eruption, photosensitivity.
Skin and subcutaneous tissue disorders Urticaria, pruritus, drug rash, angioedema, allergic skin reactions, fixed drug eruption, photosensitivity. Some of the patients mentioned in these case reports had an underlying neuromuscular disorder see section 4. Other common indications for using a syringe driver in palliative care include the treatment of nausea and vomiting, excessive respiratory secretions, cycllizine agitation or restlessness.
We’d love to send you our articles and latest news by email, giving you the best opportunity to stay up to date with expert written health and lifestyle content. Peripheral anticholinergic symptoms include, dry mouth, nose and throat, blurred vision, tachycardia and urinary retention.
Syrjnge should not drive or operate machinery until they have determined their own response. Driving and skilled tasks Drowsiness may affect performance of skilled tasks e.